About the PRCs

Select an Option

About the PRCs

The Biodefense Proteomics Research Centers are among several initiatives developed by NIAID to provide comprehensive genomic, proteomic, and bioinformatic resources to the scientific community. By integrating multiple approaches to science, NIAID is providing resources for basic and applied research to rapidly address the Nation's biodefense needs.

It is anticipated that the research programs will discover targets for potential candidates for the next generation of vaccines, therapeutics, and diagnostics. In order to accomplish this, the Biodefense Proteomics Research Program has the following goals:

to characterize proteomes of pathogens and/or host cells;
to identify proteins associated with the biology of the microbes;
to elucidate mechanisms of microbial pathogenesis; and
to further understand innate and adaptive immune responses to infectious agents and non-immune mediated host responses that contribute to microbial pathogenesis.

This program will use existing proteomics technologies, augment existing technologies, create novel proteomics approaches, and perform early stage validation of targets. It will focus on NIAID Category A-C priority pathogens and other microorganisms responsible for emerging and/or re-emerging diseases.

The related initiative, Administrative Resource for Biodefense Proteomic Centers will design, develop, and maintain a publicly accessible Web site that contains data and technology protocols generated by each Proteomics Research Center. This database will serve as a central information source for reagents and validated protein targets.

Proteomic Research Centers

Albert Einstein College of Medicine (Einstein)
PI is Dr. Ruth Angeletti; Topic: Toxoplasma gondii, Cryptosporidium parvum
Caprion Proteomics Inc.(Caprion)
PI is Dr. Eustache Paramithiotis; Topic: Brucella abortus
Harvard Institute of Proteomics (HIP)
PI is Dr. Joshua LaBaer; Topic: Bacillus anthracis, Vibrio cholerae
Myriad Genetics (Myriad)
PI is Dr. Jerry S. Lanchbury; Topic: Bacillus anthracis, Yersinia pestis, Francisella tularensis, vaccinia
Pacific Northwest National Laboratory (PNNL)
PI is Dr. Richard Smith; Topic: Salmonella typhimurium, Salmonella typhi, vaccinia, monkeypox
The Scripps Research Institute - FSPS (FSPS)
PI is Dr. Peter Kuhn; Topic: SARS-CoV
University of Michigan (U-M)
PI is Dr. Phillip Hanna; Topic: Bacillus anthracis



LOGIN	ACCESSIBILITY	PRIVACY STATEMENT	SITE HELP	CONTACT INFO	NIAID	NIH	DHHS